| 11-Jun-25 |
| Chairs: John Axford and Róisín O'Flaherty |
| 14:00-14:20 |
Welcome Session with President Eeva Leinonen |
| Plenary Lecture 1 |
| 14:20-15:00 |
Yvette Van Kyook, Amsterdam UMC, The Netherlands |
Sialylation of the tumor microenvironment and its impact on immune suppression |
| 15:00-15:20 |
SLT 1: Sandra van Vliet, Amsterdam UMC, The Netherlands |
Site-specific reprogramming of the tumor-immune microenvironment through sialic acids |
| 15:20-15:30 |
SPT 1: Jack Cheeseman, Ludger Ltd, The United Kingdom |
Potential sialic acid and glycomic biomarkers of cardiovascular disease |
| 15:30-15:40 |
SPT 2: Aert Scheper, CÚRAM Research Ireland Centre for Medical Devices, Ireland |
IVD regeneration in a canine nucleus pulposus injury model – using sialylation inhibitor-loaded injectable hydrogels for IVD repair |
| 15:40-16:00 |
Coffee Break |
| Chairs: Katrine T. Schjolfager and Joseph J Barchi Jr |
| Plenary Lecture 2 |
| 16:00-16:40 |
Matthew Wilson, KU Leuven, Belgium |
Revising dolichol biosynthesis: an unexpected detour |
| 16:40-17:00 |
SLT 2: Frederic Bard, Centre de Recherche en Cancérologie de Marseille, France |
ER O-glycosylation in synovial fibroblasts drives cartilage degradation |
| 17:00-17:10 |
SPT 3: Mark Robinson, Maynooth University, Ireland |
Assessing glycosylation enzyme expression in activated innate lympocyte subpopulations. |
| 17:10-17:20 |
SPT 4: Qianyue Zhang, Leiden University Medical Center, The Netherlands |
Obesity affects the adipocyte glycosylation machinery and N-glycan profiles in mice |
| 17:20-17:40 |
SLT 3: Nele Festjens, VIB-Ugent Center for Medical Biotechnology, Belgium. |
N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity |
| 19:00 |
Committee Dinner |
| June 12th 2025 Session 3: Mucosal Glycobiology: Roles of Mucins and O-Glycans in Disease |
| Chairs: Henrik Clausen and Frederic Bard |
| Plenary Lecture 3 |
| 09:30-10:10 |
Gunnar C Hansson, University of Gothenburg, Sweden |
The highly glycosylated mucins form different types of mucus that both inhibit and cause disease of the intestine and lung |
| 10:10-10:30 |
SLT 4: Rajindra Aryal, Harvard Medical School, USA |
Unravelling the role of extended O-glycans in human biology: insight from the pathogenic variants of C1GALT1C1 |
| 10:30-10:40 |
SPT 5: Rebecca Bennion, Cancer Research Center of Marseille, France |
Defining ER-localised O-glycosylation in pancreatic ductal adenocarcinoma |
| 10:40-10:50 |
SPT 6: Joseph J Barchi Jr, Centre for Cancer Research |
(IR)Rational Design of Mucin Glycopeptides as Tumor Immunotherapeutic Agents |
| 10:50-11:10 |
Coffee Break |
| Chairs: Claudine Kieda and Gordon Greville |
| 11:10-11:30 |
SPONSORED TALK |
| 11:30-11:40 |
SPT 7: Ines Moreira, Hannover Medical School, Germany |
Neolactotetraosylceramide enables urinary detection of bladder cancer |
| 11:40-11:50 |
SPT 8: Rafaela Abrantes, University of Porto (i3S), Portugal |
Novel CAR T formulations targeting tumor-associated glycoepitopes: a new strategy for solid tumors |
| Plenary Lecture 4 |
| 11:50-12:30 |
Ana Magalhaes, University of Porto (i3S), Portugal |
Heparan and chondroitin sulfate proteoglycans cellular switch and functional implications for gastric cancer |
| 12:30-15:00 |
Poster Session + Lunch + Wine reception |
| Chairs: Celso Reis and Noortje de Haan |
| 15:00-15:20 |
SLT 5: Yusuke Mimura, NHO Yamaguchi Ube Medical Center, Japan |
Galactosylated and afucosylated glycoforms of intravenous immunoglobulin control inflammation |
| 15:20-15:30 |
SPT 9: Cengiz Goekeri, Charité - Universitätsmedizin Berlin, Germany |
Unravelling the role of terminal fucosylation in Pneumococcal Pneumonia |
| 15:30-15:40 |
SPT 10: Daniel Hornikx, Radboud University, The Netherlands |
Dissecting Siglec-15 ligand expression in thyroid cancer |
| 15:40-15:50 |
SPT 11: Joseph Zaia, Boston University School of Medicine, USA |
An on-slide tissue digestion multi-omic data-independent acquisition approach to identify the role of glycosylation in Alzheimer's Disease with Lewy body pathology |
| 15:50-16:00 |
SPT 12: Shasha Li, Queen's University Belfast, United Kingdom |
Development and testing of novel small molecule inhibitors for the manipulation of IgE glycosylation |
| 16:00-16:30 |
Coffee Break and Photoshoot (Outdoor Amphitheatre) |
| 16:30-17:50 |
In Interview with Prof John Axford: Prof Pauline Rudd |
| 19:00 |
Conference Dinner (Pugin Hall, South Campus) |
| 13th June 2025 |
| Chairs: Abhay Pandit and Yvette Van Kyook |
| Plenary Lecture 5 |
| 09:30-10:10 |
Ryan Flynn Harvard University, USA |
GlycoRNA biology on the cell surface |
| 10:10-10:30 |
SLT 6: Michelle Kilcoyne University of Galway, Ireland |
Glycomics microarrays for profiling host immune-pathogen interactions and measuring adaptive immune response |
| 10:30-10:40 |
SPT 13: Joana Gomes University of Porto (i3S), Portugal |
ST6GAL1 role in antibody therapy response and immune evasion of colorectal cancer |
| 10:40-10:50 |
SPT 14: Radka Fahey (Saldova) NIBRT, Ireland |
Endometriosis specific vaginal microbiota links to urine and serum N-glycome |
| 10:50-11:10 |
Coffee Break |
| Chairs: Nico Callewaert and Joeseph Zaia |
| 11:10-11:30 |
SPONSORED TALK 2 |
| 11:30-11:40 |
SPT 15: Leander Meuris, VIB-UGent Center for Medical Biotechnology, Belgium |
Validation of the glycomics-based glycocirrhotest as predictor of risk of hcc development in cirrhosis |
| 11:40-11:50 |
SPT 16: Andreea Cislaru, Maynooth University, Ireland |
Chemoenzymatic strategy for single glycoform monoclonal antibody production |
| Plenary Lecture 6 |
| 11:50-12:30 |
Noortje de Haan, Amsterdam UMC, The Netherlands |
Cell Surface Glycoproteomics to Study the Differential Glycosylation of Cancer Glycoproteins |
| 12:30-12:40 |
Prize Winners Ceremony
Chairs: Emily Harlin and Nico Callwaert |
| 12:40-15:00 |
Lunch and Biodiversity Walk (free event, requires booking here) |
| Chairs: Radka Saldova and Sandra von Vliet |
| Plenary Lecture 7 |
| 15:00-15:40 |
Andres Salumets Karolinska Institute, Sweden |
Glycobiology of human conception |
| 15:40-15:50 |
SPT 17: Julia Vreugdenhil Genos Ltd, Croatia |
De novo sequencing of human milk oligosaccharides using IM-MS |
| 15:50-16:10 |
SLT 7: Richard Drake Medical University of South Carolina, USA. |
Detection of immune cell glycosylation as an indicator of metabolic activity in the tumour tissue microenvironment using N-glycan and multiplexed-IHC mass spectrometry imaging |
| 16:10-16:20 |
Closing Ceremony
Chairs: Róisín O'Flaherty and Jenner 17 Chair |
