| 11 June 2025 Rising Stars Satellite Conference | ||
| 09:30-12:30 | MU Science Museum, South Campus (requires pre-booking here) | Rising Stars Satellite Conference |
| 10:00-12:00 | MU South Campus (requires pre-booking here) | Tour of Russell Library |
| 13:00-14:00 | Registration and Coffee Break | |
SLT=Selected Talk, SPT=Speed Talk
| 11-Jun-25 | ||
| Session 1: Sialic Acid Biology: From Tumour Immunity to Tissue Engineering | ||
| Chairs: John Axford and Róisín O'Flaherty | ||
| 14:00-14:20 | Welcome Session with President Eeva Leinonen | |
| Plenary Lecture 1 | ||
| 14:20-15:00 | Yvette Van Kyook, Amsterdam UMC, The Netherlands | Sialylation of the tumor microenvironment and its impact on immune suppression |
| 15:00-15:20 | SLT 1: Sandra van Vliet, Amsterdam UMC, The Netherlands | Site-specific reprogramming of the tumor-immune microenvironment through sialic acids |
| 15:20-15:30 | SPT 1: Jack Cheeseman, Ludger Ltd, The United Kingdom | Potential sialic acid and glycomic biomarkers of cardiovascular disease |
| 15:30-15:40 | SPT 2: Aert Scheper, CÚRAM Research Ireland Centre for Medical Devices, Ireland | IVD regeneration in a canine nucleus pulposus injury model – using sialylation inhibitor-loaded injectable hydrogels for IVD repair |
| 15:40-16:00 | Coffee Break | |
| Session 2: Glycosylation Pathways: Mechanisms and Modulators | ||
| Chairs: Katrine T. Schjolfager and Joseph J Barchi Jr | ||
| Plenary Lecture 2 | ||
| 16:00-16:40 | Matthew Wilson, KU Leuven, Belgium | Revising dolichol biosynthesis: an unexpected detour |
| 16:40-17:00 | SLT 2: Frederic Bard, Centre de Recherche en Cancérologie de Marseille, France | ER O-glycosylation in synovial fibroblasts drives cartilage degradation |
| 17:00-17:10 | SPT 3: Mark Robinson, Maynooth University, Ireland | Assessing glycosylation enzyme expression in activated innate lympocyte subpopulations. |
| 17:10-17:20 | SPT 4: Qianyue Zhang, Leiden University Medical Center, The Netherlands | Obesity affects the adipocyte glycosylation machinery and N-glycan profiles in mice |
| 17:20-17:40 | SLT 3: Nele Festjens, VIB-Ugent Center for Medical Biotechnology, Belgium. | N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity |
| 19:00 | Committee Dinner | |
| June 12th 2025 Session 3: Mucosal Glycobiology: Roles of Mucins and O-Glycans in Disease | ||
| Chairs: Henrik Clausen and Frederic Bard | ||
| Plenary Lecture 3 | ||
| 09:30-10:10 | Gunnar C Hansson, University of Gothenburg, Sweden | The highly glycosylated mucins form different types of mucus that both inhibit and cause disease of the intestine and lung |
| 10:10-10:30 | SLT 4: Rajindra Aryal, Harvard Medical School, USA | Unravelling the role of extended O-glycans in human biology: insight from the pathogenic variants of C1GALT1C1 |
| 10:30-10:40 | SPT 5: Rebecca Bennion, Cancer Research Center of Marseille, France | Defining ER-localised O-glycosylation in pancreatic ductal adenocarcinoma |
| 10:40-10:50 | SPT 6: Joseph J Barchi Jr, Centre for Cancer Research | (IR)Rational Design of Mucin Glycopeptides as Tumor Immunotherapeutic Agents |
| 10:50-11:10 | Coffee Break | |
| Session 4: Cancer Glycobiology | ||
| Chairs: Claudine Kieda and Gordon Greville | ||
| 11:10-11:30 | SPONSORED TALK | |
| 11:30-11:40 | SPT 7: Ines Moreira, Hannover Medical School, Germany | Neolactotetraosylceramide enables urinary detection of bladder cancer |
| 11:40-11:50 | SPT 8: Rafaela Abrantes, University of Porto (i3S), Portugal | Novel CAR T formulations targeting tumor-associated glycoepitopes: a new strategy for solid tumors |
| Plenary Lecture 4 | ||
| 11:50-12:30 | Ana Magalhaes, University of Porto (i3S), Portugal | Heparan and chondroitin sulfate proteoglycans cellular switch and functional implications for gastric cancer |
| 12:30-15:00 | Poster Session + Lunch + Wine reception | |
| Session 5: Glycosylation and Immune Modulation in Disease | ||
| Chairs: Celso Reis and Noortje de Haan | ||
| 15:00-15:20 | SLT 5: Yusuke Mimura, NHO Yamaguchi Ube Medical Center, Japan | Galactosylated and afucosylated glycoforms of intravenous immunoglobulin control inflammation |
| 15:20-15:30 | SPT 9: Cengiz Goekeri, Charité - Universitätsmedizin Berlin, Germany | Unravelling the role of terminal fucosylation in Pneumococcal Pneumonia |
| 15:30-15:40 | SPT 10: Daniel Hornikx, Radboud University, The Netherlands | Dissecting Siglec-15 ligand expression in thyroid cancer |
| 15:40-15:50 | SPT 11: Joseph Zaia, Boston University School of Medicine, USA | An on-slide tissue digestion multi-omic data-independent acquisition approach to identify the role of glycosylation in Alzheimer's Disease with Lewy body pathology |
| 15:50-16:00 | SPT 12: Shasha Li, Queen's University Belfast, United Kingdom | Development and testing of novel small molecule inhibitors for the manipulation of IgE glycosylation |
| 16:00-16:30 | Coffee Break and Photoshoot (Outdoor Amphitheatre) | |
| 16:30-17:50 | In Interview with Prof John Axford: Prof Pauline Rudd | |
| 19:00 | Conference Dinner (Pugin Hall, South Campus) | |
| 13th June 2025 | ||
| Session 6: Glycoimmune Modulation: Mechanistic Insights from GlycoRNA to Host-Pathogen Interactions | ||
| Chairs: Abhay Pandit and Yvette Van Kyook | ||
| Plenary Lecture 5 | ||
| 09:30-10:10 | Ryan Flynn Harvard University, USA | GlycoRNA biology on the cell surface |
| 10:10-10:30 | SLT 6: Michelle Kilcoyne University of Galway, Ireland | Glycomics microarrays for profiling host immune-pathogen interactions and measuring adaptive immune response |
| 10:30-10:40 | SPT 13: Joana Gomes University of Porto (i3S), Portugal | ST6GAL1 role in antibody therapy response and immune evasion of colorectal cancer |
| 10:40-10:50 | SPT 14: Radka Fahey (Saldova) NIBRT, Ireland | Endometriosis specific vaginal microbiota links to urine and serum N-glycome |
| 10:50-11:10 | Coffee Break | |
| Session 7: Glycobiotechnology | ||
| Chairs: Nico Callewaert and Joeseph Zaia | ||
| 11:10-11:30 | SPONSORED TALK 2 | |
| 11:30-11:40 | SPT 15: Leander Meuris, VIB-UGent Center for Medical Biotechnology, Belgium | Validation of the glycomics-based glycocirrhotest as predictor of risk of hcc development in cirrhosis |
| 11:40-11:50 | SPT 16: Andreea Cislaru, Maynooth University, Ireland | Chemoenzymatic strategy for single glycoform monoclonal antibody production |
| Plenary Lecture 6 | ||
| 11:50-12:30 | Noortje de Haan, Amsterdam UMC, The Netherlands | Cell Surface Glycoproteomics to Study the Differential Glycosylation of Cancer Glycoproteins |
| 12:30-12:40 | Prize Winners Ceremony Chairs: Emily Harlin and Nico Callwaert |
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| 12:40-15:00 | Lunch and Biodiversity Walk (free event, requires booking here) | |
| Session 8: Glycosylation in Human Development and Disease | ||
| Chairs: Radka Saldova and Sandra von Vliet | ||
| Plenary Lecture 7 | ||
| 15:00-15:40 | Andres Salumets Karolinska Institute, Sweden | Glycobiology of human conception |
| 15:40-15:50 | SPT 17: Julia Vreugdenhil Genos Ltd, Croatia | De novo sequencing of human milk oligosaccharides using IM-MS |
| 15:50-16:10 | SLT 7: Richard Drake Medical University of South Carolina, USA. | Detection of immune cell glycosylation as an indicator of metabolic activity in the tumour tissue microenvironment using N-glycan and multiplexed-IHC mass spectrometry imaging |
| 16:10-16:20 | Closing Ceremony Chairs: Róisín O'Flaherty and Jenner 17 Chair |
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